The seat carries out research and technology transfer in different areas of chemistry, materials and energetics




Research activity in Milan concerns the properties and technology of structural and functional materials, fluid dynamics, and diagnostics or reactive systems.


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ICMATE-Genoa has expertise in the fields of physical chemistry of interfaces and in the preparation of powders, ceramics and composites of functional oxides.


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ICMATE-Lecco is one of the few centers in Italy able to operate in the secondary metallurgy of advanced metallic materials


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Editor’s choice in Journal of Cultural Heritage, Volume 45, 2020

Mona Lisa, the icon of Western painting, painted at the very beginning of the 16th century by Leonardo da Vinci, needs no introduction.
In Master Verrocchio’s workshop, Leonardo learned a method of preparing paintings which included making a drawing on the paper and then transferring it onto the wood board by spolvero. In this technique, already described by Cennini in the 15th century, the drawing is first perforated with a needle, producing holes along the contours, and then placed on the plank; the subsequent application of a powdered black pigment leaves a series of black dots.
Differently from other portraits painted by Leonardo, for instance, The Lady with an Ermine, Ginevra de’ Benci and La Belle Ferronnière, where the spolvero had been detected, no traces of this technique were discovered in Mona Lisa.
The traditional means of observing spolvero under paintings is to use IR photography and IR reflectography. Despite the advancement in this techniques, also recent studies did not evidence the presence of this technique in Mona Lisa.

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The increasing demand for alternatives to fossil fuels lead scientists to search for new materials to be used as energy vectors. Nowadays, it is generally accepted that hydrogen is the best solution to this issue. One of the reasons why hydrogen is not yet commonly employed in everyday life lies in the lack of a safe, practical and effective method for its storage. A possible solution that meets the above requirements is given by intermetallic hydrides, which can be charged with hydrogen at high-pressure to form stable hydrides, then releasing hydrogen by heating the host intermetallic.

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Studies of the physico-chemical properties of the solid-liquid interfaces at high temperatures, in particular wetting and reactivity, and of the related mechanisms.

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  • Synthesis and biological evaluation of metallic compounds of Technetium-99m and Rhenium-188 for theranostic applications in Nuclear Medicine
    Radiopharmaceuticals (RP) are drugs containing radioactive isotopes of certain elements, used in nuclear medicine for diagnosis and/or therapy. The systemic administration of 'target' specific RPs, which provides a specific distribution of the radionuclide to tumor sites is an interesting opportunity for the diagnosis and the therapy of tumors/metastases. The development of a 'target-specific' RP is conditioned by the availability of appropriate radionuclides, efficient labelling procedures that leaves unaltered the biological property of the native molecule and reliable targeting vector.
  • Copper (I) complexes as potential anticancer agents
    Since the discovery of the antitumor activity of cisplatin cis-[PtCl2(NH3)2] for the treatment of several human tumors, thousands of platinum and other metal–based compounds have been tested for their potential antitumor properties in the last 40 years. Aim of this search is to overcome the drawbacks of Pt(II) derivatives such low specificity, high toxicity and inherited and/or acquired drug resistance.

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